{"id":15441,"date":"2019-08-27T09:38:49","date_gmt":"2019-08-27T08:38:49","guid":{"rendered":"https:\/\/kinderwunschaerztin.de\/leistungen\/miscarriage-diagnostics\/"},"modified":"2026-10-06T15:17:30","modified_gmt":"2026-10-06T14:17:30","slug":"miscarriage-diagnostics","status":"publish","type":"leistungen","link":"https:\/\/kinderwunschaerztin.de\/en\/services\/diagnostics\/miscarriage-diagnostics\/","title":{"rendered":"Mis\u00adcar\u00adriage Diag\u00adnos\u00adtics"},"content":{"rendered":"\n
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Why a mis\u00adcar\u00adriage can occur<\/h2>\n\n\n\n

Mis\u00adcar\u00adriages are com\u00admon and, espe\u00adcial\u00adly in ear\u00adly preg\u00adnan\u00adcy, are usu\u00adal\u00adly caused by ran\u00addom chro\u00admo\u00adso\u00admal changes in the embryo. A sin\u00adgle mis\u00adcar\u00adriage there\u00adfore often remains a one-time event and does not auto\u00admat\u00adi\u00adcal\u00adly mean that an ill\u00adness or dis\u00ador\u00adder is present. In many cas\u00ades, no fur\u00adther diag\u00adnos\u00adtic work-up is required after a sin\u00adgle mis\u00adcar\u00adriage. Many women sub\u00adse\u00adquent\u00adly become preg\u00adnant again and expe\u00adri\u00adence a nor\u00admal\u00adly pro\u00adgress\u00ading preg\u00adnan\u00adcy with the birth of a healthy child. <\/p>\n\n\n\n

If mis\u00adcar\u00adriages occur repeat\u00aded\u00adly, a tar\u00adget\u00aded eval\u00adu\u00ada\u00adtion may be use\u00adful. Pos\u00adsi\u00adble influ\u00adenc\u00ading fac\u00adtors range from genet\u00adic and anatom\u00adi\u00adcal caus\u00ades to hor\u00admon\u00adal con\u00addi\u00adtions and cer\u00adtain clot\u00adting or autoim\u00admune dis\u00ador\u00adders. It is not always pos\u00adsi\u00adble to iden\u00adti\u00adfy a clear cause. The aim of diag\u00adnos\u00adtics is to iden\u00adti\u00adfy pos\u00adsi\u00adble risk fac\u00adtors and plan the next steps indi\u00advid\u00adu\u00adal\u00adly. <\/p>\n\n\n\n

The immune sys\u00adtem plays an impor\u00adtant role in implan\u00adta\u00adtion, ear\u00adly pla\u00adcen\u00adtal devel\u00adop\u00adment, and main\u00adtain\u00ading a preg\u00adnan\u00adcy. Cer\u00adtain autoim\u00admune dis\u00adeases and immuno\u00adlog\u00adi\u00adcal changes can be asso\u00adci\u00adat\u00aded with an increased risk of mis\u00adcar\u00adriage. These include, for exam\u00adple, antiphos\u00adpho\u00adlipid syn\u00addrome, cer\u00adtain autoim\u00admune thy\u00adroid dis\u00adeases, or pre\u00advi\u00adous\u00adly undi\u00adag\u00adnosed coeli\u00adac dis\u00adease. In addi\u00adtion, oth\u00ader changes in the mater\u00adnal immune response are being inves\u00adti\u00adgat\u00aded as pos\u00adsi\u00adble influ\u00adenc\u00ading fac\u00adtors in recur\u00adrent mis\u00adcar\u00adriages. <\/p>\n\n\n\n

Espe\u00adcial\u00adly in cas\u00ades of recur\u00adrent mis\u00adcar\u00adriages with no iden\u00adti\u00adfi\u00adable cause to date, fur\u00adther immuno\u00adlog\u00adi\u00adcal diag\u00adnos\u00adtics may there\u00adfore be use\u00adful in select\u00aded sit\u00adu\u00ada\u00adtions. We assess which tests are actu\u00adal\u00adly help\u00adful on an indi\u00advid\u00adual basis, tak\u00ading into account your med\u00adical his\u00adto\u00adry and pre\u00advi\u00adous find\u00adings. We also con\u00adsid\u00ader that the sci\u00aden\u00adtif\u00adic evi\u00addence for indi\u00advid\u00adual immuno\u00adlog\u00adi\u00adcal tests varies. <\/p>\n\n\n\n

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Who may ben\u00ade\u00adfit from fur\u00adther mis\u00adcar\u00adriage diag\u00adnos\u00adtics<\/h3>\n\n\n\n
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\n\"Logo\n\n\n\nWomen with recur\u00adrent mis\u00adcar\u00adriages<\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
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Recur\u00adrent mis\u00adcar\u00adriage is defined as the loss of two or more preg\u00adnan\u00adcies. Even after two mis\u00adcar\u00adriages, fur\u00adther diag\u00adnos\u00adtics are often advisable\u2014depending on age, med\u00adical his\u00adto\u00adry, and indi\u00advid\u00adual risk fac\u00adtors. As the num\u00adber of pre\u00advi\u00adous mis\u00adcar\u00adriages increas\u00ades, the risk of anoth\u00ader preg\u00adnan\u00adcy loss also ris\u00ades. <\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\"Logo\n\n\n\nWomen or cou\u00adples with cer\u00adtain pre-exist\u00ading con\u00addi\u00adtions<\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
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Cer\u00adtain pre-exist\u00ading con\u00addi\u00adtions can increase the risk of mis\u00adcar\u00adriage or play an impor\u00adtant role in an indi\u00advid\u00adual eval\u00adu\u00ada\u00adtion. These include, for exam\u00adple, thy\u00adroid dys\u00adfunc\u00adtion, poor\u00adly con\u00adtrolled dia\u00adbetes mel\u00adli\u00adtus, cer\u00adtain autoim\u00admune dis\u00adeases such as antiphos\u00adpho\u00adlipid syn\u00addrome or coeli\u00adac dis\u00adease, as well as oth\u00ader con\u00addi\u00adtions that can affect the course of preg\u00adnan\u00adcy. We also take gynae\u00adco\u00adlog\u00adi\u00adcal con\u00addi\u00adtions such as endometrio\u00adsis or changes in the uterus into account in the indi\u00advid\u00adual assess\u00adment. <\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\n\"Logo\n\n\n\nWomen of advanced age who wish to con\u00adceive<\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
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As age increas\u00ades, the risk of mis\u00adcar\u00adriage ris\u00ades sig\u00adnif\u00adi\u00adcant\u00adly. Data from the Ger\u00adman IVF Reg\u00adistry show this asso\u00adci\u00ada\u00adtion: In younger women, the mis\u00adcar\u00adriage rate is around 15%, but by age 40 it is already about one third. After that, it increas\u00ades marked\u00adly with each addi\u00adtion\u00adal year of age and is around two thirds or high\u00ader from age 45.
The main rea\u00adson is the increas\u00ading like\u00adli\u00adhood of chro\u00admo\u00adso\u00admal changes in the eggs\u2014and there\u00adfore in the result\u00ading embryos\u2014as age increas\u00ades. At the same time, both egg num\u00adber and egg qual\u00adi\u00adty decline. In cas\u00ades of recur\u00adrent mis\u00adcar\u00adriages and an ongo\u00ading wish to con\u00adceive, time\u00adly eval\u00adu\u00ada\u00adtion is there\u00adfore par\u00adtic\u00adu\u00adlar\u00adly advis\u00adable as age increas\u00ades, in order to iden\u00adti\u00adfy pos\u00adsi\u00adble caus\u00ades and plan the next steps indi\u00advid\u00adu\u00adal\u00adly. <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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Expert assess\u00adment for recur\u00adrent mis\u00adcar\u00adriages<\/h2>\n\n\n\n

Recur\u00adrent mis\u00adcar\u00adriages can have dif\u00adfer\u00adent caus\u00ades. These include hor\u00admon\u00adal fac\u00adtors such as thy\u00adroid or meta\u00adbol\u00adic dis\u00ador\u00adders, genet\u00adic changes, anatom\u00adi\u00adcal abnor\u00admal\u00adi\u00adties of the uterus, cer\u00adtain clot\u00adting and autoim\u00admune dis\u00ador\u00adders, or oth\u00ader immuno\u00adlog\u00adi\u00adcal fac\u00adtors. Age and the asso\u00adci\u00adat\u00aded egg and embryo qual\u00adi\u00adty also play an impor\u00adtant role. How\u00adev\u00ader, it is not always pos\u00adsi\u00adble to iden\u00adti\u00adfy a clear cause\u2014often sev\u00ader\u00adal fac\u00adtors come togeth\u00ader. <\/p>\n\n\n\n

This makes care\u00adful med\u00adical assess\u00adment of pre\u00advi\u00adous preg\u00adnan\u00adcies and all avail\u00adable find\u00adings all the more impor\u00adtant. Tar\u00adget\u00aded diag\u00adnos\u00adtics can help iden\u00adti\u00adfy pos\u00adsi\u00adble risk fac\u00adtors and derive indi\u00advid\u00adu\u00adal\u00adly appro\u00adpri\u00adate next steps. And even after sev\u00ader\u00adal mis\u00adcar\u00adriages, in many cas\u00ades there is still a good chance of a suc\u00adcess\u00adful preg\u00adnan\u00adcy and the birth of a healthy child. <\/p>\n\n\n\n

Overview of diag\u00adnos\u00adtic pro\u00adce\u00addures<\/h3>\n\n\n\n

Diag\u00adnos\u00adtics are used to specif\u00adi\u00adcal\u00adly clar\u00adi\u00adfy pos\u00adsi\u00adble caus\u00ades and risk fac\u00adtors for recur\u00adrent mis\u00adcar\u00adriages. Which tests are appro\u00adpri\u00adate depends on your per\u00adson\u00adal med\u00adical his\u00adto\u00adry and pre\u00advi\u00adous find\u00adings. <\/p>\n\n\n\n

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\nANATOMICAL DIAGNOSTICS<\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
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Anatom\u00adi\u00adcal changes of the uterus are found in about 5% of all women, but are sig\u00adnif\u00adi\u00adcant\u00adly more com\u00admon in women with recur\u00adrent miscarriages\u2014around 10\u201315%. These include, for exam\u00adple, a uter\u00adine sep\u00adtum or oth\u00ader con\u00adgen\u00adi\u00adtal forms. Using high-res\u00ado\u00adlu\u00adtion ultra\u00adsound and 3D ultra\u00adsound, we can assess the shape of the uterus and, in par\u00adtic\u00adu\u00adlar, the uter\u00adine cav\u00adi\u00adty. <\/p>\n\n\n\n

Find\u00adings such as a con\u00adgen\u00adi\u00adtal uter\u00adine sep\u00adtum, fibroids, polyps, or adhe\u00adsions can affect implan\u00adta\u00adtion or the course of a preg\u00adnan\u00adcy. If indi\u00adcat\u00aded, hys\u00adteroscopy may also be use\u00adful. This allows changes in the uter\u00adine cav\u00adi\u00adty to be assessed par\u00adtic\u00adu\u00adlar\u00adly pre\u00adcise\u00adly and\u2014where pos\u00adsi\u00adble and appropriate\u2014treated direct\u00adly. <\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\nCoag\u00adu\u00adla\u00adtion diag\u00adnos\u00adtics<\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
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Cer\u00adtain blood clot\u00adting dis\u00ador\u00adders can be asso\u00adci\u00adat\u00aded with recur\u00adrent mis\u00adcar\u00adriages and preg\u00adnan\u00adcy com\u00adpli\u00adca\u00adtions. Antiphos\u00adpho\u00adlipid syn\u00addrome (APS) is of par\u00adtic\u00adu\u00adlar importance\u2014an autoim\u00admune dis\u00adease in which cer\u00adtain anti\u00adbod\u00adies can affect blood clot\u00adting and pla\u00adcen\u00adtal devel\u00adop\u00adment. For eval\u00adu\u00ada\u00adtion, so-called antiphos\u00adpho\u00adlipid anti\u00adbod\u00adies are specif\u00adi\u00adcal\u00adly test\u00aded in the blood. <\/p>\n\n\n\n

Depend\u00ading on your per\u00adson\u00adal and fam\u00adi\u00adly his\u00adto\u00adry, oth\u00ader acquired or inher\u00adit\u00aded changes in blood clot\u00adting may also be includ\u00aded in the diag\u00adnos\u00adtic work-up. We decide which coag\u00adu\u00adla\u00adtion para\u00adme\u00adters are appro\u00adpri\u00adate in your indi\u00advid\u00adual sit\u00adu\u00ada\u00adtion based on your pre\u00advi\u00adous preg\u00adnan\u00adcies, pos\u00adsi\u00adble risk fac\u00adtors, and any exist\u00ading find\u00adings. <\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\nGenet\u00adic diag\u00adnos\u00adtics<\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
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Genet\u00adic changes are among the most com\u00admon caus\u00ades of ear\u00adly mis\u00adcar\u00adriages. Often, these are ran\u00addom changes in the num\u00adber or struc\u00adture of the embryo\u2019s chro\u00admo\u00adsomes, the risk of which increas\u00ades with the woman\u2019s age. <\/p>\n\n\n\n

In some cas\u00ades, how\u00adev\u00ader, genet\u00adic changes in the par\u00adents can also play a role\u2014even if both are com\u00adplete\u00adly healthy. In about 2\u20135% of cou\u00adples with recur\u00adrent mis\u00adcar\u00adriages, a so-called bal\u00adanced chro\u00admo\u00adso\u00admal rearrange\u00adment is found, often a translo\u00adca\u00adtion. In this case, the entire genet\u00adic mate\u00adr\u00adi\u00adal is present, but indi\u00advid\u00adual chro\u00admo\u00adsome seg\u00adments are arranged dif\u00adfer\u00adent\u00adly. For the car\u00adri\u00ader, this usu\u00adal\u00adly has no health con\u00adse\u00adquences; how\u00adev\u00ader, dur\u00ading the for\u00adma\u00adtion of egg or sperm cells, an unfavourable dis\u00adtri\u00adb\u00adu\u00adtion of chro\u00admo\u00adsomes can occur, increas\u00ading the risk of mis\u00adcar\u00adriage. <\/p>\n\n\n\n

Fur\u00adther eval\u00adu\u00ada\u00adtion may there\u00adfore include a chro\u00admo\u00adsome analy\u00adsis of both par\u00adents. In addi\u00adtion, genet\u00adic test\u00ading of preg\u00adnan\u00adcy tis\u00adsue can pro\u00advide impor\u00adtant clues about pos\u00adsi\u00adble caus\u00ades. We work with spe\u00adcialised human genet\u00adics insti\u00adtutes for this pur\u00adpose. <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

Male fac\u00adtor and sperm qual\u00adi\u00adty<\/h3>\n\n\n\n

The male fac\u00adtor can also play an impor\u00adtant role in recur\u00adrent mis\u00adcar\u00adriages and should always be includ\u00aded in the joint eval\u00adu\u00ada\u00adtion. In addi\u00adtion to stan\u00addard sperm para\u00adme\u00adters, sperm DNA integri\u00adty in par\u00adtic\u00adu\u00adlar, as well as the man\u2019s age, pre-exist\u00ading con\u00addi\u00adtions, and lifestyle, can influ\u00adence repro\u00adduc\u00adtive health. <\/p>\n\n\n\n

A semen analy\u00adsis<\/a> ini\u00adtial\u00adly pro\u00advides infor\u00adma\u00adtion about sperm count, motil\u00adi\u00adty, and mor\u00adphol\u00ado\u00adgy. In addi\u00adtion, espe\u00adcial\u00adly in cas\u00ades of recur\u00adrent mis\u00adcar\u00adriages, a DNA frag\u00admen\u00adta\u00adtion test may be use\u00adful. This exam\u00adines the pro\u00adpor\u00adtion of sperm with increased DNA strand breaks. Ele\u00advat\u00aded DNA frag\u00admen\u00adta\u00adtion can be asso\u00adci\u00adat\u00aded, among oth\u00ader things, with oxida\u00adtive stress, smok\u00ading, over\u00adweight, inflam\u00adma\u00adtion, a varic\u00ado\u00adcele, or increas\u00ading pater\u00adnal age, and may be linked to an increased risk of mis\u00adcar\u00adriage. <\/p>\n\n\n\n

For this rea\u00adson, in mis\u00adcar\u00adriage diag\u00adnos\u00adtics we do not only assess the woman, but also include sperm qual\u00adi\u00adty and poten\u00adtial\u00adly mod\u00adi\u00adfi\u00adable risk fac\u00adtors in the man.<\/p>\n\n\n\n

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\nImmuno\u00adlog\u00adi\u00adcal diag\u00adnos\u00adtics<\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
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The immune sys\u00adtem plays an impor\u00adtant role in implan\u00adta\u00adtion, pla\u00adcen\u00adtal devel\u00adop\u00adment, and main\u00adtain\u00ading a preg\u00adnan\u00adcy. Cer\u00adtain autoim\u00admune dis\u00adeases and changes in the mater\u00adnal immune response may be asso\u00adci\u00adat\u00aded with recur\u00adrent mis\u00adcar\u00adriages. <\/p>\n\n\n\n

Estab\u00adlished immuno\u00adlog\u00adi\u00adcal caus\u00ades include, in par\u00adtic\u00adu\u00adlar, antiphos\u00adpho\u00adlipid syn\u00addrome (APS). Depend\u00ading on your his\u00adto\u00adry, fur\u00adther indi\u00adca\u00adtors of autoim\u00admune dis\u00adease may also be inves\u00adti\u00adgat\u00aded, such as thy\u00adroid autoan\u00adti\u00adbod\u00adies, anti\u00adnu\u00adclear anti\u00adbod\u00adies (ANA), or pre\u00advi\u00adous\u00adly undi\u00adag\u00adnosed coeli\u00adac dis\u00adease. <\/p>\n\n\n\n

In select\u00aded sit\u00adu\u00ada\u00adtions, extend\u00aded repro\u00adduc\u00adtive immunol\u00ado\u00adgy diag\u00adnos\u00adtics may also be con\u00adsid\u00adered. This can include, for exam\u00adple, test\u00ading var\u00adi\u00adous immune cell pop\u00adu\u00adla\u00adtions and nat\u00adur\u00adal killer cells (NK cells) and\u2014depending on the clin\u00adi\u00adcal question\u2014other immuno\u00adlog\u00adi\u00adcal con\u00adstel\u00adla\u00adtions such as KIR and HLA char\u00adac\u00adter\u00adis\u00adtics. <\/p>\n\n\n\n

Not all immuno\u00adlog\u00adi\u00adcal tests are equal\u00adly well estab\u00adlished sci\u00aden\u00adtif\u00adi\u00adcal\u00adly, and not every abnor\u00admal lab\u00ado\u00adra\u00adto\u00adry val\u00adue is auto\u00admat\u00adi\u00adcal\u00adly the cause of a mis\u00adcar\u00adriage. There\u00adfore, we select tests indi\u00advid\u00adu\u00adal\u00adly based on your med\u00adical his\u00adto\u00adry and pre\u00advi\u00adous find\u00adings and always inter\u00adpret the results in the over\u00adall con\u00adtext. For spe\u00adcialised analy\u00adses, we work with expe\u00adri\u00adenced immunol\u00ado\u00adgy lab\u00ado\u00adra\u00adto\u00adries. <\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\nHor\u00admon\u00adal Diag\u00adnos\u00adtics<\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
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Hor\u00admones play an impor\u00adtant role in egg mat\u00adu\u00adra\u00adtion, the build-up of the uter\u00adine lin\u00ading, and the ear\u00adly devel\u00adop\u00adment of a preg\u00adnan\u00adcy. In cas\u00ades of recur\u00adrent mis\u00adcar\u00adriages, we there\u00adfore specif\u00adi\u00adcal\u00adly include pos\u00adsi\u00adble hor\u00admon\u00adal and meta\u00adbol\u00adic influ\u00adenc\u00ading fac\u00adtors in the diag\u00adnos\u00adtic work-up.
The thy\u00adroid plays a par\u00adtic\u00adu\u00adlar\u00adly impor\u00adtant role. Both under\u00adac\u00adtive and over\u00adac\u00adtive thy\u00adroid func\u00adtion can affect the cycle and the course of preg\u00adnan\u00adcy. In addi\u00adtion to the TSH lev\u00adel, free thy\u00adroid hor\u00admones and thy\u00adroid autoan\u00adti\u00adbod\u00adies may also be mea\u00adsured depend\u00ading on your his\u00adto\u00adry. <\/p>\n\n\n\n

Cycle and ovu\u00adla\u00adtion dis\u00ador\u00adders as well as poly\u00adcys\u00adtic ovary syn\u00addrome (PCOS) can also be asso\u00adci\u00adat\u00aded with an increased risk of mis\u00adcar\u00adriage. In PCOS, in addi\u00adtion to hor\u00admon\u00adal changes, meta\u00adbol\u00adic fac\u00adtors such as insulin resis\u00adtance often play a role. <\/p>\n\n\n\n

Prog\u00ades\u00adterone is of cen\u00adtral impor\u00adtance for the uter\u00adine lin\u00ading and main\u00adtain\u00ading preg\u00adnan\u00adcy, espe\u00adcial\u00adly after ovu\u00adla\u00adtion and in ear\u00adly preg\u00adnan\u00adcy. Depend\u00ading on the clin\u00adi\u00adcal ques\u00adtion, the sec\u00adond half of the cycle and prog\u00ades\u00adterone pro\u00adduc\u00adtion may there\u00adfore also be assessed. As prog\u00ades\u00adterone lev\u00adels fluc\u00adtu\u00adate sig\u00adnif\u00adi\u00adcant\u00adly in the nat\u00adur\u00adal cycle, results are always eval\u00adu\u00adat\u00aded in the con\u00adtext of the cycle pat\u00adtern and the oth\u00ader find\u00adings.

We deter\u00admine which hor\u00admon\u00adal tests are appro\u00adpri\u00adate on an indi\u00advid\u00adual basis, based on your med\u00adical his\u00adto\u00adry, your cycle, and any exist\u00ading find\u00adings.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n

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<\/div>\n\n\n\n
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Sup\u00adport after a mis\u00adcar\u00adriage: The path to an indi\u00advid\u00adual eval\u00adu\u00ada\u00adtion<\/h2>\n\n\n\n

With mod\u00adern diag\u00adnos\u00adtics and many years of expe\u00adri\u00adence, we sup\u00adport you in eval\u00adu\u00adat\u00ading recur\u00adrent mis\u00adcar\u00adriages.<\/p>\n\n\n\n

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Step by step through mis\u00adcar\u00adriage diag\u00adnos\u00adtics<\/h4>\n<\/div>\n<\/div>\n\n\n\n
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  1. \n

    Ini\u00adtial Con\u00adsul\u00adta\u00adtion<\/h4>\n\n\n\n

    At the begin\u00adning, we take time to review your med\u00adical his\u00adto\u00adry, the course of your pre\u00advi\u00adous preg\u00adnan\u00adcies, and pos\u00adsi\u00adble risk fac\u00adtors. Togeth\u00ader, we assess which tests are appro\u00adpri\u00adate in your per\u00adson\u00adal sit\u00adu\u00ada\u00adtion.  <\/p>\n\n\n\nMake an appoint\u00adment<\/a>\n<\/li>\n\n\n\n

  2. \n

    Blood tests<\/h4>\n\n\n\n

    Depend\u00ading on your his\u00adto\u00adry and pre\u00advi\u00adous find\u00adings, var\u00adi\u00adous lab\u00ado\u00adra\u00adto\u00adry tests may be use\u00adful. These include, for exam\u00adple, hor\u00admone lev\u00adels, thy\u00adroid para\u00adme\u00adters<\/a>, cer\u00adtain autoan\u00adti\u00adbod\u00adies, and select\u00aded coag\u00adu\u00adla\u00adtion and immuno\u00adlog\u00adi\u00adcal para\u00adme\u00adters. <\/p>\n<\/li>\n\n\n\n

  3. \n

    Ultra\u00adsound and fur\u00adther exam\u00adi\u00adna\u00adtions<\/h4>\n\n\n\n

    Using high-res\u00ado\u00adlu\u00adtion ultra\u00adsound, we can assess the uterus and its struc\u00adture. Depend\u00ading on the clin\u00adi\u00adcal ques\u00adtion, a 3D ultra\u00adsound or, in some cas\u00ades, hys\u00adteroscopy may also be use\u00adful. <\/p>\n<\/li>\n\n\n\n

  4. \n

    Genet\u00adic tests (if required)<\/h4>\n\n\n\n

    In cas\u00ades of recur\u00adrent mis\u00adcar\u00adriages, a chro\u00admo\u00adsome analy\u00adsis of both part\u00adners may be use\u00adful. If preg\u00adnan\u00adcy tis\u00adsue is avail\u00adable, genet\u00adic test\u00ading of this tis\u00adsue can also pro\u00advide impor\u00adtant clues about the cause of a mis\u00adcar\u00adriage. <\/p>\n<\/li>\n\n\n\n

  5. \n

    Bring\u00ading the find\u00adings togeth\u00ader<\/h4>\n\n\n\n

    We care\u00adful\u00adly eval\u00adu\u00adate all results and dis\u00adcuss them with you to obtain a com\u00adpre\u00adhen\u00adsive pic\u00adture of the pos\u00adsi\u00adble caus\u00ades.<\/p>\n<\/li>\n\n\n\n

  6. \n

    Indi\u00advid\u00adual rec\u00adom\u00admen\u00adda\u00adtion<\/h4>\n\n\n\n

    Based on the results, we dis\u00adcuss togeth\u00ader which fur\u00adther steps are appropriate\u2014from tar\u00adget\u00aded treat\u00adment of indi\u00advid\u00adual risk fac\u00adtors to indi\u00advid\u00adual sup\u00adport when try\u00ading to con\u00adceive again or dur\u00ading a sub\u00adse\u00adquent preg\u00adnan\u00adcy.<\/p>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n

    \n
    \n\"Union\"\n\n\n\n

    Try\u00ading to con\u00adceive after recur\u00adrent mis\u00adcar\u00adriages: Pos\u00adsi\u00adble treat\u00adment approach\u00ades<\/h2>\n\n\n\n

    Which treat\u00adment is appro\u00adpri\u00adate after recur\u00adrent mis\u00adcar\u00adriages depends on the pos\u00adsi\u00adble caus\u00ades, the pre\u00advi\u00adous test results, and your per\u00adson\u00adal fer\u00adtil\u00adi\u00adty his\u00adto\u00adry. It is not always pos\u00adsi\u00adble to find a clear cause, and not every abnor\u00admal find\u00ading requires treat\u00adment. There\u00adfore, togeth\u00ader with you, we decide which ther\u00ada\u00adpeu\u00adtic mea\u00adsures are appro\u00adpri\u00adate in your indi\u00advid\u00adual sit\u00adu\u00ada\u00adtion. <\/p>\n\n\n\n

    Depend\u00ading on the cause and indi\u00advid\u00adual sit\u00adu\u00ada\u00adtion, dif\u00adfer\u00adent ther\u00ada\u00adpeu\u00adtic approach\u00ades may be con\u00adsid\u00adered to specif\u00adi\u00adcal\u00adly sup\u00adport a preg\u00adnan\u00adcy.<\/p>\n<\/div>\n\n\n\n

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    \n
    \n
    \nHORMONAL S<\/strong>UPPORT<\/strong><\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
    \n
    \n

    Hor\u00admon\u00adal dis\u00ador\u00adders such as under\u00adac\u00adtive or over\u00adac\u00adtive thy\u00adroid func\u00adtion, ele\u00advat\u00aded pro\u00adlactin lev\u00adels, or cer\u00adtain meta\u00adbol\u00adic and cycle dis\u00ador\u00adders can be treat\u00aded in a tar\u00adget\u00aded man\u00adner. Prog\u00ades\u00adterone also plays an impor\u00adtant role for the uter\u00adine lin\u00ading and main\u00adtain\u00ading ear\u00adly preg\u00adnan\u00adcy. Whether addi\u00adtion\u00adal prog\u00ades\u00adterone sup\u00adple\u00admen\u00adta\u00adtion is advis\u00adable is decid\u00aded based on your med\u00adical his\u00adto\u00adry, your cycle, and the course of a sub\u00adse\u00adquent preg\u00adnan\u00adcy. <\/p>\n\n\n\n

    \nMake an appoint\u00adment<\/span><\/span><\/a>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
    \n
    \nAnti\u00adco\u00adag\u00adu\u00adlant ther\u00ada\u00adpy<\/strong><\/strong><\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
    \n
    \n

    In cer\u00adtain con\u00adfirmed clot\u00adting dis\u00ador\u00adders, anti\u00adco\u00adag\u00adu\u00adlant treatment\u2014for exam\u00adple with heparin or low-dose acetyl\u00adsal\u00adi\u00adcylic acid\u2014may be use\u00adful. Whether and which treat\u00adment is rec\u00adom\u00admend\u00aded depends on the spe\u00adcif\u00adic find\u00adings and your med\u00adical his\u00adto\u00adry. <\/p>\n\n\n\n

    \nMake an appoint\u00adment<\/span><\/span><\/a>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
    \n
    \nImmunomod\u00adu\u00adla\u00adto\u00adry treat\u00adment<\/strong><\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
    \n
    \n

    In cas\u00ades of recur\u00adrent mis\u00adcar\u00adriages, immuno\u00adlog\u00adi\u00adcal fac\u00adtors may also play a role in some cas\u00ades. If the extend\u00aded immuno\u00adlog\u00adi\u00adcal diag\u00adnos\u00adtics show rel\u00ade\u00advant abnor\u00admal\u00adi\u00adties, we assess these in a dif\u00adfer\u00aden\u00adti\u00adat\u00aded way and in the con\u00adtext of your fer\u00adtil\u00adi\u00adty his\u00adto\u00adry and the oth\u00ader find\u00adings. <\/p>\n\n\n\n

    Depend\u00ading on the indi\u00advid\u00adual sit\u00adu\u00ada\u00adtion, dif\u00adfer\u00adent immunomod\u00adu\u00adla\u00adto\u00adry treat\u00adment approach\u00ades may be con\u00adsid\u00adered. Which ther\u00ada\u00adpy may be appro\u00adpri\u00adate depends on the type of abnor\u00admal\u00adi\u00adty, pos\u00adsi\u00adble comor\u00adbidi\u00adties, and pre\u00advi\u00adous preg\u00adnan\u00adcy cours\u00ades. We dis\u00adcuss with you the var\u00adi\u00adous options, their poten\u00adtial ben\u00ade\u00adfits and risks, as well as the respec\u00adtive sci\u00aden\u00adtif\u00adic data and evi\u00addence. Togeth\u00ader with you, we care\u00adful\u00adly weigh whether and which immunomod\u00adu\u00adla\u00adto\u00adry treat\u00adment may be appro\u00adpri\u00adate in your per\u00adson\u00adal sit\u00adu\u00ada\u00adtion. <\/p>\n\n\n\n

    \nMake an appoint\u00adment<\/span><\/span><\/a>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
    \n
    \nSur\u00adgi\u00adcal treat\u00adment of the uterus<\/strong><\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
    \n
    \n

    If changes in the uterus are identified\u2014for exam\u00adple cer\u00adtain polyps, fibroids, adhe\u00adsions, or a mal\u00adfor\u00adma\u00adtion of the uter\u00adine cavity\u2014surgical treat\u00adment may be use\u00adful. Whether an inter\u00adven\u00adtion is rec\u00adom\u00admend\u00aded depends on the type and extent of the find\u00adings. <\/p>\n\n\n\n

    \nMake an appoint\u00adment<\/span><\/span><\/a>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
    \n
    \nIndi\u00advid\u00adual sup\u00adport in ear\u00adly preg\u00adnan\u00adcy<\/strong><\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
    \n
    \n

    After pre\u00advi\u00adous mis\u00adcar\u00adriages, a new preg\u00adnan\u00adcy is often asso\u00adci\u00adat\u00aded with great uncer\u00adtain\u00adty. Close mon\u00adi\u00adtor\u00ading and per\u00adson\u00adal care in the first weeks of preg\u00adnan\u00adcy pro\u00advide reas\u00adsur\u00adance and enable us to assess the devel\u00adop\u00adment of the preg\u00adnan\u00adcy ear\u00adly and respond indi\u00advid\u00adu\u00adal\u00adly if abnor\u00admal\u00adi\u00adties occur. <\/p>\n\n\n\n

    \nMake an appoint\u00adment<\/span><\/span><\/a>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
    \n
    \nFur\u00adther fer\u00adtil\u00adi\u00adty treat\u00adments<\/strong><\/span>\n\n\n\n<\/span><\/span><\/span>\n<\/div>\n\n\n\n
    \n
    \n

    IVF or ICSI<\/a> may be use\u00adful if, in addi\u00adtion to recur\u00adrent mis\u00adcar\u00adriages, oth\u00ader fac\u00adtors are present that make it more dif\u00adfi\u00adcult to achieve preg\u00adnan\u00adcy. We assess indi\u00advid\u00adu\u00adal\u00adly whether repro\u00adduc\u00adtive med\u00adical treat\u00adment offers an advan\u00adtage, based on your med\u00adical his\u00adto\u00adry and the diag\u00adnos\u00adtic results. <\/p>\n\n\n\n

    \nMake an appoint\u00adment<\/span><\/span><\/a>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n
    \n
    <\/div>\n\n\n\n
    \n

    Ten\u00adder Lov\u00ading Care: Com\u00adpas\u00adsion\u00adate sup\u00adport after a mis\u00adcar\u00adriage<\/h2>\n\n\n\n

    After recur\u00adrent mis\u00adcar\u00adriages, a new preg\u00adnan\u00adcy is often asso\u00adci\u00adat\u00aded with many<\/ins> wor\u00adries and fears<\/ins>. As part of what is known as Ten\u00adder Lov\u00ading Care, we there\u00adfore sup\u00adport you par\u00adtic\u00adu\u00adlar\u00adly close\u00adly, espe\u00adcial\u00adly in the first weeks of pregnancy\u2014with reg\u00adu\u00adlar ultra\u00adsound checks, per\u00adson\u00adal con\u00adsul\u00adta\u00adtions, and con\u00adtin\u00adu\u00adous med\u00adical care. <\/p>\n\n\n\n

    Stud\u00adies sug\u00adgest that such inten\u00adsive and sup\u00adport\u00adive care after recur\u00adrent mis\u00adcar\u00adriages can have a pos\u00adi\u00adtive effect on the fur\u00adther course of preg\u00adnan\u00adcy. At the same time, the reg\u00adu\u00adlar check-ups pro\u00advide reas\u00adsur\u00adance and enable us to assess the devel\u00adop\u00adment of the preg\u00adnan\u00adcy ear\u00adly and respond indi\u00advid\u00adu\u00adal\u00adly if need\u00aded. <\/p>\n<\/div>\n<\/div>\n\n

    \n
    \n\"Close-up\n\n\n\n

    Per\u00adson\u00adal sup\u00adport after recur\u00adrent mis\u00adcar\u00adriages<\/h2>\n\n\n\n

    <\/p>\n\n\n\nArrange a con\u00adsul\u00adta\u00adtion appoint\u00adment<\/a>\n<\/div>\n\n\n\n

    \n