What is PRP Treat­ment for Infer­til­i­ty?

PRP (Platelet Rich Plas­ma) is being inves­ti­gat­ed in repro­duc­tive med­i­cine as a com­ple­men­tary treat­ment par­tic­u­lar­ly for thin endometri­um and reduced ovar­i­an func­tion. The sci­en­tif­ic evi­dence varies depend­ing on the area of appli­ca­tion and is not yet suf­fi­cient to rec­om­mend PRP as an estab­lished stan­dard treat­ment. There­fore, we use PRP exclu­sive­ly after indi­vid­ual med­ical con­sul­ta­tion and care­ful con­sid­er­a­tion.

PRP is obtained from the patien­t’s own blood and is rich in platelets and endoge­nous growth fac­tors. For treat­ment, a small amount of blood is drawn and processed using a spe­cial­ized pro­ce­dure.

In repro­duc­tive med­i­cine, PRP is being inves­ti­gat­ed pri­mar­i­ly for two dif­fer­ent appli­ca­tions: intrauter­ine infu­sion to sup­port the endometri­um and injec­tion into the ovaries in cas­es of reduced ovar­i­an func­tion. For both pro­ce­dures, a poten­tial ther­a­peu­tic ben­e­fit is being inves­ti­gat­ed; how­ev­er, they are not cur­rent­ly among the estab­lished stan­dard treat­ments in repro­duc­tive med­i­cine.

  • PRP to Sup­port the Uterus (Endometri­um)

    In intrauter­ine PRP treat­ment, the processed platelet-rich plas­ma is intro­duced into the uter­ine cav­i­ty via a thin catheter. This pro­ce­dure is being inves­ti­gat­ed par­tic­u­lar­ly in cas­es of repeat­ed­ly thin or inad­e­quate­ly devel­oped endometri­um and recur­rent implan­ta­tion fail­ure.


    Sev­er­al ran­dom­ized stud­ies and meta-analy­ses are now avail­able show­ing promis­ing results. Par­tic­u­lar­ly in patients with thin endometri­um, improved endome­tri­al devel­op­ment has been observed with PRP. Some stud­ies also show high­er implan­ta­tion, clin­i­cal preg­nan­cy, and in some cas­es live birth rates.

    How­ev­er, exist­ing stud­ies dif­fer in terms of patient selec­tion, PRP prepa­ra­tion, dosage, and appli­ca­tion. PRP there­fore remains an unestab­lished stan­dard ther­a­py but can be con­sid­ered as a com­ple­men­tary treat­ment option in select­ed patients after indi­vid­ual med­ical con­sul­ta­tion.

  • PRP to Sup­port the Ovaries

    In intrao­var­i­an PRP, the processed platelet-rich plas­ma is inject­ed direct­ly into the ovar­i­an tis­sue under ultra­sound guid­ance. This pro­ce­dure is being inves­ti­gat­ed par­tic­u­lar­ly in women with reduced ovar­i­an reserve or poor response to hor­mon­al stim­u­la­tion (Poor Ovar­i­an Response).


    Indi­vid­ual stud­ies report changes in AMH val­ues, fol­li­cle devel­op­ment, or oocyte yield. How­ev­er, whether PRP can actu­al­ly influ­ence ovar­i­an reserve or increase the prob­a­bil­i­ty of live birth is not yet suf­fi­cient­ly estab­lished. Par­tic­u­lar­ly for women with pre­ma­ture ovar­i­an insuf­fi­cien­cy (POI), restora­tion of ovar­i­an func­tion can­not cur­rent­ly be promised.

When PRP Treat­ment May Be Appro­pri­ate

PRP is not a rou­tine fer­til­i­ty treat­ment. How­ev­er, in select­ed patients it can be con­sid­ered as a com­ple­men­tary ther­a­peu­tic option. Whether treat­ment is appro­pri­ate depends on the indi­vid­ual base­line sit­u­a­tion and whether PRP is to be used on the endometri­um or ovaries.

PRP on the endometri­um may be con­sid­ered par­tic­u­lar­ly in cas­es of:

  • repeat­ed­ly thin or inad­e­quate­ly devel­oped endometri­um
  • recur­rent implan­ta­tion fail­ure after IVF or ICSI
  • sig­nif­i­cant changes or dam­age to the endometri­um, for exam­ple in Ash­er­man syn­drome

PRP on the ovaries may be dis­cussed in select­ed cas­es of:

  • reduced ovar­i­an reserve, for exam­ple with low AMH val­ue
  • poor response to pre­vi­ous hor­mon­al stim­u­la­tion treat­ments (Poor Ovar­i­an Response)
  • pre­ma­ture ovar­i­an insuf­fi­cien­cy (POI)

The sci­en­tif­ic evi­dence dif­fers depend­ing on the area of appli­ca­tion: For intrauter­ine PRP, par­tic­u­lar­ly in cas­es of thin endometri­um, sev­er­al stud­ies with pos­i­tive results are now avail­able. For PRP on the ovaries, the clin­i­cal ben­e­fit is less well estab­lished. There­fore, we indi­vid­u­al­ly assess whether PRP treat­ment may be appro­pri­ate in your sit­u­a­tion.

Risks and Lim­i­ta­tions of PRP Treat­ment

  • Tem­po­rary Dis­com­fort
    After treat­ment, mild pain, low­er abdom­i­nal cramp­ing, or minor bleed­ing may occur tem­porar­i­ly. With PRP treat­ment of the ovaries, dis­com­fort may be sim­i­lar to that fol­low­ing fol­li­cle aspi­ra­tion.
  • Risks of Intrauter­ine PRP
    The intro­duc­tion of PRP into the uterus is per­formed via a thin catheter and is min­i­mal­ly inva­sive over­all. Very rarely, heav­ier bleed­ing or infec­tions may occur.
  • Risks of Intrao­var­i­an PRP
    Treat­ment of the ovaries is per­formed by trans­vagi­nal punc­ture under ultra­sound guid­ance. This car­ries risks sim­i­lar to oocyte retrieval, includ­ing bleed­ing, infec­tions, or injury to adja­cent struc­tures. When per­formed under seda­tion, the asso­ci­at­ed gen­er­al risks apply.
  • No Guar­an­teed Effect
    Not every patient ben­e­fits from PRP treat­ment. Whether and to what extent endometri­um, ovar­i­an response, or treat­ment out­come will change can­not be reli­ably pre­dict­ed indi­vid­u­al­ly.
  • Still Lim­it­ed Sci­en­tif­ic Evi­dence
    PRP is not yet among the estab­lished stan­dard treat­ments in repro­duc­tive med­i­cine. For intrauter­ine PRP, par­tic­u­lar­ly in cas­es of thin endometri­um, sev­er­al stud­ies with pos­i­tive results are now avail­able. For PRP on the ovaries, the evi­dence is sig­nif­i­cant­ly more lim­it­ed. Fur­ther high-qual­i­ty stud­ies are need­ed to defin­i­tive­ly assess ben­e­fit, opti­mal appli­ca­tion, and long-term safe­ty.
Consultation with Dr. med. Corinna Mann at the fertility center in Munich regarding fertility treatment. Blood draw for hormone and fertility diagnostics at the private practice in Munich. A couple looking at an ultrasound image together—full of hope and anticipation.

Our Med­ical Assess­ment of PRP Treat­ment

Advanced option

PRP has been used in var­i­ous areas of med­i­cine for many years. In repro­duc­tive med­i­cine as well, inten­sive research is being con­duct­ed to deter­mine whether the endoge­nous growth fac­tors con­tained in platelet-rich plas­ma can be used ther­a­peu­ti­cal­ly.

Appli­ca­tion to the endometri­um is cur­rent­ly par­tic­u­lar­ly inter­est­ing. In recent years, sev­er­al ran­dom­ized stud­ies and meta-analy­ses have been pub­lished show­ing pos­i­tive results par­tic­u­lar­ly for repeat­ed­ly thin endometrium—both regard­ing endome­tri­al devel­op­ment and in some cas­es preg­nan­cy and live birth rates. At the same time, the stud­ies remain het­ero­ge­neous, so PRP can­not cur­rent­ly be con­sid­ered an estab­lished stan­dard ther­a­py.

We assess PRP treat­ment of the ovaries more cau­tious­ly. While there are ini­tial inter­est­ing stud­ies on patients with reduced ovar­i­an reserve or poor response to hor­mon­al stim­u­la­tion, whether this can rel­e­vant­ly improve ovar­i­an func­tion or par­tic­u­lar­ly the chance of live birth is not yet suf­fi­cient­ly estab­lished.

For us, PRP is there­fore a pos­si­ble com­ple­men­tary treat­ment option for care­ful­ly select­ed patients. We dis­cuss trans­par­ent­ly what cur­rent stud­ies show, where uncer­tain­ties remain, and whether treat­ment appears med­ical­ly appro­pri­ate in the indi­vid­ual sit­u­a­tion.

Inte­grat­ing PRP Indi­vid­u­al­ly into Treat­ment

Depend­ing on the treat­ment goal pur­sued, the tim­ing of PRP appli­ca­tion dif­fers. We coor­di­nate treat­ment indi­vid­u­al­ly with the cycle, find­ings, and fur­ther fer­til­i­ty treat­ment.

PRP FOR ENDOMETRIAL DEVELOPMENT

In cas­es of repeat­ed­ly thin or inad­e­quate­ly devel­oped endometri­um, PRP can be used specif­i­cal­ly in the first half of the cycle. Depend­ing on endome­tri­al find­ings and cycle pro­gres­sion, we usu­al­ly intro­duce the processed PRP two to three times at inter­vals of approx­i­mate­ly two to three days between cycle days 5 and 12 via a thin catheter into the uter­ine cav­i­ty. Endome­tri­al devel­op­ment is mon­i­tored by ultra­sound and, if nec­es­sary, hor­mone mea­sure­ments.

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PRP to Sup­port Implan­ta­tion

When PRP is to be used in con­nec­tion with embryo trans­fer, intrauter­ine appli­ca­tion typ­i­cal­ly occurs approx­i­mate­ly one to two days before the planned trans­fer. The goal is to sup­port the endometri­um imme­di­ate­ly before the implan­ta­tion phase. Depend­ing on the indi­vid­ual sit­u­a­tion, appli­ca­tion can be inte­grat­ed into a nat­ur­al or hor­mon­al­ly pre­pared trans­fer cycle.

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PRP on the Ovaries


In IVF or ICSI treat­ment, intrao­var­i­an PRP can be per­formed dur­ing an already planned fol­li­cle aspi­ra­tion. The processed PRP is inject­ed direct­ly into the ovar­i­an tis­sue under ultra­sound guid­ance. If no oocyte retrieval is planned, PRP injec­tion can be per­formed sep­a­rate­ly in the ear­ly fol­lic­u­lar phase. Whether ovar­i­an PRP treat­ment appears appro­pri­ate and at what time it is per­formed is deter­mined indi­vid­u­al­ly based on ovar­i­an reserve, pre­vi­ous stim­u­la­tion cours­es, and fur­ther treat­ment plan­ning.

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Process of PRP Treat­ment for Infer­til­i­ty

In our fer­til­i­ty cen­ter, we guide you through all steps of PRP treat­ment in a struc­tured and trans­par­ent man­ner. The exact pro­ce­dure depends on whether PRP is used to sup­port the ovaries, uterus, or as part of IVF/ICSI.

  1. Med­ical Con­sul­ta­tion & Treat­ment Plan­ning

    A com­pre­hen­sive med­ical con­sul­ta­tion takes place at the begin­ning. We review your fer­til­i­ty his­to­ry, pre­vi­ous treat­ments, and your per­son­al goals.

    Addi­tion­al­ly, we per­form ultra­sound exam­i­na­tions and—depending on the question—hormonal diag­nos­tics (e.g., AMH val­ue). This allows us to assess whether PRP treat­ment is med­ical­ly appro­pri­ate for your per­son­al sit­u­a­tion. We then dis­cuss togeth­er whether and at what time PRP should be used.

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  2. PRP Col­lec­tion and Prepa­ra­tion

    On the treat­ment day, a small amount of blood is drawn. The blood is processed using a spe­cial­ized cen­trifu­ga­tion pro­ce­dure to pro­duce platelet-rich plas­ma (PRP) with a high con­cen­tra­tion of endoge­nous growth fac­tors. Pro­cess­ing is per­formed under con­trolled clean room con­di­tions and the high­est hygien­ic stan­dards.

  3. PRP on the Endometri­um

    The pre­pared PRP is intro­duced into the uter­ine cav­i­ty via a thin catheter.

    The appli­ca­tion is com­pa­ra­ble to insem­i­na­tion or embryo trans­fer and does not require anes­the­sia. Depend­ing on the treat­ment goal, PRP can be applied mul­ti­ple times dur­ing endome­tri­al devel­op­ment or specif­i­cal­ly before a planned embryo trans­fer.

  4. PRP on the Ovaries

    The PRP is inject­ed direct­ly into the ovar­i­an tis­sue using a fine nee­dle under ultra­sound guid­ance.

    In IVF or ICSI treat­ment, this can be per­formed dur­ing an already planned fol­li­cle aspi­ra­tion. If no oocyte retrieval is planned, treat­ment can be per­formed as a sep­a­rate punc­ture. In this case, it is usu­al­ly per­formed under brief seda­tion.

  5. After Treat­ment

    You can usu­al­ly resume your dai­ly activ­i­ties imme­di­ate­ly after the intrauter­ine PRP pro­ce­dure.

    After PRP treat­ment of the ovaries, you will ini­tial­ly remain in our cen­ter for a short obser­va­tion peri­od and should rest phys­i­cal­ly on the day of treat­ment.

  6. Fur­ther Treat­ment Course

    How to pro­ceed from there depends on the treat­ment goal.

    Pos­si­bil­i­ties include fur­ther PRP appli­ca­tions to the endometri­um, hor­mon­al stim­u­la­tion, or a planned embryo trans­fer. We coor­di­nate fur­ther treat­ment and nec­es­sary mon­i­tor­ing indi­vid­u­al­ly with you.

Close-up of a flower vase in the bright practice atmosphere at the fertility center in Munich for a relaxed consultation.

Why Choose Us for PRP Treat­ment

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  • Spe­cial­ized Repro­duc­tive Med­i­cine Expe­ri­ence

    PRP treat­ment is per­formed by spe­cial­ists in Gyne­co­log­i­cal Endocrinol­o­gy and Repro­duc­tive Med­i­cine. We indi­vid­u­al­ly assess whether PRP can be appro­pri­ate­ly used in your sit­u­a­tion and which form of appli­ca­tion is suit­able.

  • PRP Specif­i­cal­ly Inte­grat­ed into Your Treat­ment

    Whether for endome­tri­al devel­op­ment, before embryo trans­fer, or as intrao­var­i­an appli­ca­tion: We coor­di­nate tim­ing and imple­men­ta­tion with your cycle and fur­ther fer­til­i­ty treat­ment. Direct inte­gra­tion into IVF or ICSI treat­ment is also pos­si­ble.

  • Mod­ern Lab­o­ra­to­ry Med­i­cine

    Blood pro­cess­ing is per­formed under con­trolled clean room con­di­tions and accord­ing to high qual­i­ty stan­dards.

  • Evi­dence-Based and Trans­par­ent Con­sul­ta­tion

    The sci­en­tif­ic evi­dence on PRP con­tin­ues to evolve and dif­fers depend­ing on the area of appli­ca­tion. We dis­cuss trans­par­ent­ly with you what cur­rent stud­ies show, where lim­i­ta­tions and uncer­tain­ties exist, and what you can real­is­ti­cal­ly expect from treat­ment.

Cur­rent Research Sta­tus on PRP Treat­ment

The sci­en­tif­ic evi­dence on PRP con­tin­ues to evolve and dif­fers sig­nif­i­cant­ly depend­ing on the area of appli­ca­tion.

  • PRP on the Endometri­um

    Sev­er­al ran­dom­ized stud­ies and meta-analy­ses are now avail­able for intrauter­ine PRP. Par­tic­u­lar­ly for thin endometri­um, stud­ies show improved endome­tri­al devel­op­ment; some meta-analy­ses also report high­er clin­i­cal preg­nan­cy and in some cas­es live birth rates.

    For recur­rent implan­ta­tion fail­ure as well, cur­rent meta-analy­ses of ran­dom­ized stud­ies show pos­i­tive results regard­ing clin­i­cal preg­nan­cy and live birth. How­ev­er, stud­ies con­tin­ue to dif­fer in terms of patient selec­tion, PRP prepa­ra­tion, dosage, and tim­ing of appli­ca­tion.

    Despite increas­ing­ly pos­i­tive study results for intrauter­ine PRP, treat­ment is not yet rec­om­mend­ed by inter­na­tion­al pro­fes­sion­al soci­eties as an estab­lished rou­tine treat­ment.

  • PRP on the Ovaries

    For intrao­var­i­an PRP, the evi­dence is sig­nif­i­cant­ly less clear. Stud­ies and meta-analy­ses report in some cas­es improve­ments in AMH, antral fol­li­cle count, or oocyte yield in women with reduced ovar­i­an reserve or Poor Ovar­i­an Response.

    How­ev­er, cur­rent analy­ses of con­trolled and ran­dom­ized stud­ies show no con­sis­tent evi­dence of improve­ment in preg­nan­cy or live birth rates. Whether PRP can clin­i­cal­ly rel­e­vant­ly improve ovar­i­an func­tion there­fore remains a sub­ject of research.

Cur­rent Lit­er­a­ture:

  • Yang Y, Zhang X, Zhang Y. Platelet-rich plas­ma ther­a­py for thin endometri­um: a com­pre­hen­sive review. Archives of Gyne­col­o­gy and Obstet­rics. 2025.
  • Effi­ca­cy of platelet-rich plas­ma in the treat­ment of thin endometri­um: a meta-analy­sis of ran­dom­ized con­trolled tri­als. 2024.
  • Liang X et al. Impact of Intrauter­ine Infu­sion of Autol­o­gous Platelet-Rich Plas­ma on Assist­ed Repro­duc­tive Out­comes in Patients With Recur­rent Implan­ta­tion Fail­ure: A Meta-Analy­sis of Ran­dom­ized Con­trolled Tri­als. Repro­duc­tive Med­i­cine and Biol­o­gy. 2026.
  • Sadegh­pour S et al. Eval­u­a­tion of intrao­var­i­an injec­tion of platelet-rich plas­ma for enhanced ovar­i­an func­tion and repro­duc­tive suc­cess in women with POI and POR: a sys­tem­at­ic review and meta-analy­sis. Euro­pean Jour­nal of Med­ical Research. 2025.
  • Intrao­var­i­an Platelet-Rich Plas­ma for Women with Dimin­ished Ovar­i­an Reserve: A Sys­tem­at­ic Review and Meta-Analy­sis. 2026.
 
  
 
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What Our Patients Say

 
 
 
 
 
 
 
 
 
 
 
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 Sandra B 
 
105 days ago
 
 
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Had a very good experience, I felt very well taken care of, everyone very professional, standardized routines, can definitely recommend
  
 
 
 
 
 
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 Lauren W 
 
141 days ago
 
 
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We flew from overseas to work with Dr Mann and her team. Everyone was so kind, empathetic and extremely helpful. Everyone spoke English and made us feel very welcome. We could not have asked for better care than what we received from Dr Mann and her team. Bonus, the offices are beautiful.
  
 
 
 
 
 
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 Andrea C 
 
185 days ago
 
 
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After visiting two other fertility clinics (one of which I left in tears), I had almost lost hope of finding a place where I would truly feel heard. Then I met Dr. Sarah Comploj, and everything changed.

From the very first consultation, I felt genuinely listened to and treated as an individual. Unlike my previous experiences, where I was quickly told I needed IVF without anyone really taking the time to understand my situation or carefully review my test results, here I felt that my case truly mattered. Every step was explained thoughtfully, and my concerns were taken seriously.

What stood out the most was that I never felt like just another patient or that the focus was on money. Instead, I felt that the entire team was committed to helping me achieve my dream in the most appropriate and personal way possible.

Today, I am holding my one-month-old baby in my arms, and I will forever be grateful for the care, compassion, and expertise I received here. I can only highly recommend this clinic and Dr. Comploj 🩷
  
 
 
 
 
 
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 Viktoria O 
 
323 days ago
 
 
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Every appointment I’ve had over the last few months has been consistently informative, professional, and conducted in a personal manner. The treatment plan was explained in detail and any concerns or questions always answered. She also speaks perfect English if required. I’m impressed with how well organised the clinic is and how quickly results are processed, and last-minute appointments made available. For anyone who is going through the struggle of infertility it’s a difficult and vulnerable time, but I always felt so reassured and in good hands with Dr Mann.
  
 
 
 
 
 
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 Local R 
 
331 days ago
 
 
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A heartfelt thank you to Dr. Gerber for the exceptional support and warmth during a very sensitive journey. I always felt respected and in good hands. Truly grateful.
  
 
 
 
 
 
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 V D 
 
452 days ago
 
 
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I'm very grateful for my experience, the staff from reception to the doctors were very kind. You can feel  accompanied during the treatment. Also, overall I had a successful treatment, especially considering my age, it's a costly treatment but it's worth it. So I'm very happy for the result, my doctor was Sara Comploj.
  
 
 
 
 
 
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 Marina 
 
489 days ago
 
 
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I had a wonderful experience with the Kinderwunsch practice, and especially with dr. Corina Mann. From the very beginning, dr Mann was attentive, knowledgeable, and truly invested in helping me achieve the best possible outcome. She took the time to understand my goals and tailored my treatment plan to make sure I had the best chance of success.

Thanks to her care and expertise, I was able to maximise my results and reach my goals. I always felt supported, informed, and in the best hands. Dr Mann always answered my countless questions with a smile :) I’m incredibly grateful for her dedication and would wholeheartedly recommend her to anyone starting their fertility journey.
  
 
 
 
 
 
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 Carmencita 
 
491 days ago
 
 
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I just want to say a big thank you to the whole team of Dr. Mann and Dr. Albrecht. I felt really taking care off  in this Praxis and really can recommend everyone to go to this clinic, as here you can get at least the most possible personalization and time dedicated to you! Thanks again for your support!
  
 
 
 
 
 
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 Maria K 
 
587 days ago
 
 
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Since my doctor was busy and couldn't do the procedure herself, I had an appointment with Sarah to have my fallopian tubes checked. I was very nervous before the procedure, but it turned out to be for nothing! Sarah described and explained every step of the procedure and was extremely friendly.
  
 
 
 
 
 
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 Jay B 
 
1149 days ago
 
 
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Our multiple years-long Kinderwunsch journey was spent under the care of Dr. Mann and her Kinderwunsch practice team. Dr. Mann is not only a highly competent expert in her field, she's also empathetic and kind. She treated each appointment with a sense of being genuinely invested — listening to concerns or questions, planning for my unique treatment needs, and explaining processes or procedures without rushing (because she knows it's likely your first time going through something ... even though it might be her 40000th time). Her practice is busy and it's because she's the best. The practice team is cheerful and helpful. The waiting area is comfortable with pleasant music, flowers, and they even laid out gingerbread during Christmas time. They have a lab on-site so results are often same-day. I particularly found the technology they use to share results via email quickly so helpful. And I always felt at ease speaking in my native language and not pressured to try to keep up with unfamiliar German terminology. I'm forever grateful to have found Dr. Mann. We plan to visit soon with our new plus-one :)

- RB & JB
  
 
 
 
 
 
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 Aparna P 
 
1649 days ago
 
 
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Dr.Albrecht is really good and friendly. She is best at her own way. But reception staff is very very very worst and disappointing. They themselves book an appointment and say it’s not booked. Luckily in Doctorlib my appointment was visible. Staff is very very rude. And they respond very rudely. I can give 0 rating for Staff at reception.
  
 
 
 
 
 
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 Cindy L 
 
1670 days ago
 
 
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We had an absolutely wonderful experience with Dr. Mann. Her positive energy and competence was so reassuring and much appreciated during the potentially stressful time of trying to have a baby. I really loved how we could communicate in either English or German over complicated and sensitive reproductive matters. She took the time to answer all of our questions and offered us a wealth of information regarding the treatments. And her staff brought the same good vibes and Expertise to the practice. Some of the best and painless blood draws I’ve ever had, and they were always very responsive through emails as well as telephone communication. Online appointment system was also great. Video consults super convenient. The setting of the practice itself is an oasis of peace and calmness. As soon as I stepped through the doors I felt relaxed with the music, green plant wall, and well designed and decorated space. Technology and quality of equipment is very good. Yes, sometimes the waiting time had been 30+ minutes, but because the patient care is so excellent, I’ll be back for future treatments as needed, and would highly recommend this practice and team to anyone.
  
 
 
 
 
 
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 Raluca O 
 
1854 days ago
 
 
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I have only the best words to describe my experience at the clinic. I personally worked with Dr. Albrecht and she was amazing. Every appointment was done on time, informative and clear on what the next steps are. She offered details and support with my every question. Where I wasn’t sure of my German we swapped to English to make sure I understood everything.

The clinic is run in a very efficient way, organized, planned and as a process oriented person I loved it!
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Costs of PRP Treat­ment for Infer­til­i­ty

The cost of PRP treat­ment depends on the area in which it is used (ovaries or uterus) and whether it is per­formed inde­pen­dent­ly or as part of exist­ing fer­til­i­ty treat­ment (e.g., IVF/ICSI). It typ­i­cal­ly includes med­ical con­sul­ta­tion and diag­nos­tics, blood draw and lab­o­ra­to­ry pro­cess­ing of PRP, and the actu­al treat­ment.

To the cost overview
PRP Endometri­um — approx. 210 €

Treat­ment is per­formed on an out­pa­tient basis and is par­tic­u­lar­ly suit­able for thin endometri­um or recur­rent implan­ta­tion fail­ure. Depend­ing on the med­ical base­line sit­u­a­tion, mul­ti­ple appli­ca­tions may be appro­pri­ate.

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PRP Ovaries — approx. 665-810 €

Costs vary depend­ing on whether treat­ment is per­formed inde­pen­dent­ly or as part of oocyte retrieval. Before begin­ning, you will receive a trans­par­ent indi­vid­ual cost overview accord­ing to GOÄ.

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Notes on Billing

No fixed or flat-rate prices: We bill on the basis of the offi­cial scale of fees for doc­tors (GOÄ). Accord­ing to the GOÄ, we are not allowed to quote fixed or flat-rate prices for med­ical ser­vices. The prices men­tioned are intend­ed to pro­vide ori­en­ta­tion and are typ­i­cal for the treat­ments men­tioned.

Pos­si­ble VAT lia­bil­i­ty: Med­ical ser­vices may be sub­ject to VAT (cur­rent­ly 19%). This applies if, after diag­nos­tics have been car­ried out, no med­ical indi­ca­tion or con­firmed diag­no­sis is present and it is there­fore not a med­ical treat­ment in the strict sense. This can be the case in par­tic­u­lar with social freez­ing treat­ments, but also with the treat­ment of sin­gle moms and same-sex cou­ples.

Note on Cost Cov­er­age

We would be hap­py to pro­vide you with detailed cost infor­ma­tion for the planned treat­ment in advance. This allows you to clar­i­fy cost cov­er­age with your pri­vate health insur­ance (PKV) as best as pos­si­ble before­hand. Statu­to­ry health insur­ance (GKV) does not cov­er costs at our cen­ter.

Fre­quent­ly Asked Ques­tions about PRP Treat­ment for Infer­til­i­ty

What is PRP treat­ment?

PRP stands for “Platelet Rich Plas­ma.” For treat­ment, a small amount of the patien­t’s own blood is drawn and processed to pro­duce par­tic­u­lar­ly platelet-rich plas­ma with endoge­nous growth fac­tors. In repro­duc­tive med­i­cine, PRP is being inves­ti­gat­ed pri­mar­i­ly for treat­ment of the endometri­um and—with sig­nif­i­cant­ly more lim­it­ed evidence—for appli­ca­tion to the ovaries.

For Whom May PRP Treat­ment Be Appro­pri­ate?

Intrauter­ine PRP may be con­sid­ered par­tic­u­lar­ly in cas­es of repeat­ed­ly thin or inad­e­quate­ly devel­oped endometri­um and in select­ed cas­es of recur­rent implan­ta­tion fail­ure. Intrao­var­i­an PRP is being inves­ti­gat­ed pri­mar­i­ly in cas­es of reduced ovar­i­an reserve or poor response to pre­vi­ous stim­u­la­tion treat­ments. Whether PRP may be appro­pri­ate in your indi­vid­ual sit­u­a­tion will be dis­cussed after care­ful med­ical assess­ment.

How Do PRP on the Endometri­um and PRP on the Ovaries Dif­fer?

In intrauter­ine appli­ca­tion, PRP is intro­duced into the uter­ine cav­i­ty via a thin catheter. The goal is par­tic­u­lar­ly to sup­port endome­tri­al devel­op­ment or appli­ca­tion in con­nec­tion with embryo trans­fer.

In intrao­var­i­an treat­ment, PRP is inject­ed direct­ly into the ovar­i­an tis­sue under ultra­sound guid­ance. The two pro­ce­dures dif­fer not only in imple­men­ta­tion but also in their sci­en­tif­ic evi­dence: For PRP on the endometri­um, sev­er­al stud­ies with pos­i­tive results are now avail­able, while the clin­i­cal ben­e­fit of PRP on the ovaries is sig­nif­i­cant­ly less well estab­lished.

How Suc­cess­ful Is PRP Treat­ment?

This can­not cur­rent­ly be answered with a uni­ver­sal­ly applic­a­ble suc­cess rate. For intrauter­ine PRP, sev­er­al stud­ies and meta-analy­ses show par­tic­u­lar­ly for thin endometri­um improved endome­tri­al devel­op­ment and in some cas­es high­er preg­nan­cy and live birth rates. There are also pos­i­tive results for recur­rent implan­ta­tion fail­ure.

For intrao­var­i­an PRP, indi­vid­ual stud­ies report changes in AMH, antral fol­li­cle count, or oocyte yield. How­ev­er, whether this improves the prob­a­bil­i­ty of preg­nan­cy or live birth is not yet suf­fi­cient­ly estab­lished.

When Does PRP Treat­ment Show Its Effect?

With PRP treat­ment of the endometri­um, a pos­si­ble effect may be vis­i­ble with­in a few days in the same cycle. Fur­ther endome­tri­al devel­op­ment can be direct­ly mon­i­tored by ultra­sound.

With PRP treat­ment of the ovaries, a pos­si­ble change is expect­ed lat­er. Since fol­li­cle mat­u­ra­tion occurs over sev­er­al weeks to months, pos­si­ble effects can usu­al­ly be assessed after approx­i­mate­ly 6–12 weeks. Whether and to what extent PRP actu­al­ly influ­ences ovar­i­an func­tion is not yet sci­en­tif­i­cal­ly con­clu­sive­ly estab­lished.

Can PRP Increase Ovar­i­an Reserve?

Whether PRP can actu­al­ly improve ovar­i­an reserve is not yet estab­lished. Indi­vid­ual stud­ies report changes in AMH or antral fol­li­cle count after intrao­var­i­an PRP. How­ev­er, this does not mean that new oocytes are cre­at­ed or that age-relat­ed decline in ovar­i­an reserve can be reversed.

What are the side effects or risks?

Since PRP is obtained from the patien­t’s own blood, aller­gic reac­tions to the plas­ma itself are not expect­ed. After intrauter­ine PRP, mild bleed­ing, cramp­ing, or low­er abdom­i­nal dis­com­fort may occur tem­porar­i­ly.

Intrao­var­i­an treat­ment is more inva­sive and car­ries the gen­er­al risks of trans­vagi­nal punc­ture, par­tic­u­lar­ly bleed­ing, infec­tions, or rarely injury to adja­cent struc­tures. When treat­ment is per­formed under seda­tion, the asso­ci­at­ed gen­er­al risks apply.

When should PRP treat­ment not be per­formed?

Whether PRP treat­ment can be per­formed must be indi­vid­u­al­ly assessed. Con­traindi­ca­tions may include acute infec­tions, rel­e­vant coag­u­la­tion or platelet dis­or­ders, and cer­tain seri­ous ill­ness­es. Med­ica­tions that affect platelet func­tion or coag­u­la­tion should also be con­sid­ered before treat­ment.

Does PRP replace IVF or oth­er infer­til­i­ty treat­ments?

No. PRP is a com­ple­men­tary, not yet estab­lished treat­ment and does not replace IVF or ICSI. How­ev­er, with appro­pri­ate indi­ca­tion, PRP can be inte­grat­ed into fer­til­i­ty treat­ment or an embryo trans­fer cycle.

Does Health Insur­ance Cov­er the Cost of PRP?

PRP treat­ment is typ­i­cal­ly a self-pay ser­vice. Pos­si­ble reim­burse­ment by pri­vate health insur­ance depends on the indi­vid­ual plan and med­ical indi­ca­tion and should be clar­i­fied with the insur­ance com­pa­ny in advance.

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Herzogspitalstraße 5
80331 Munich
Germany

T: +49 89 123 595 65
F: +49 89 123 595 56
hallo@kinderwunschaerztin.de

Opening hours:
Mon: 7:00 AM–12:00 PM / 1:00–5:00 PM
Tue: 7:00 AM–8:00 PM
Wed: 7:00 AM–12:00 PM / 1:30–5:00 PM
Thu: 7:00 AM–4:30 PM
Fri: 7:00 AM–2:00 PM

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